And my original thread about it, from when it came out as an unformatted Accelerated Article Preview: bsky.app/profile/imar...
Inigo Martincorena
Excited to share our latest work in Nature. Applying single-molecule and single-cell DNA sequencing methods, we uncover an extraordinary landscape of somatic mutations in immune checkpoint genes in autoimmune B cells, suggesting that somatic mutations may be key to autoimmunity [1/n] rdcu.be/fdqbr
Nature - Polyclonal selection of immune checkpoint mutations in thyroid autoimmunity