Director of Discovery Chemistry at Stealth Medicines
www.sculpturatus.com
Evolution-Guided Pharmacology, Drug Discovery, Chemical Immunology, Aging
Kevin A. Scott
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Kevin A. Scott
"Right now, in some underfunded lab, a scientist is chasing a question that sounds pointless...a century of experience says that funding people to do this work is a good bet. If we stop making that bet, we will pay for it in cures no one will know to miss."
A subset of CysDB fragments occupies chemical space with no overlap with approved drugs — likely flat, aromatic, low-complexity chemotypes underrepresented in drug space. The overlapping subset probes cysteine sites with drug-like physicochemistry.
sculpturatus.com/surveyorchemscape