Excited to share our spatial omics from hypothal. are out in Cell Rep--with more interactive data browsing coming soon w/ UCSC single-cell browser! @kr-maynard.bsky.social @kasperdhansen.bsky.social
•Paper: www.cell.com/cell-reports...
•UCSC (demo): cells-test.gi.ucsc.edu?ds=hypothala...
9/8: The high-res spatial expression browser! Full-resolution of H&E stained tissue sections and the gene expression from them. Great for seeing neuromelanin. (One sample = one tissue section).
A large study of developing brains reveals genetic and molecular differences between males and females. The findings may help explain why neurodevelopmental conditions, including autism, occur at different rates in boys and girls.
By @giorgiag-sciwriter.bsky.social
bit.ly/4q9BsVH
Proud to announce our paper ‘Transcriptomic Analysis of the Human Habenula in Schizophrenia’ from @lieberinstitute.bsky.social is the cover article for the November issue of the American Journal of Psychiatry! 🧠#HabenulaLIBD #snRNAseq #Habenula doi.org/10.1176/appi...
10/8: Any time you see two tissue sections, the other was the preceding or subsequent 10µm of tissue cut from the same donor, because @heenadivecha.bsky.social is a beast! As is the link to the browser with all 85 tissue sections available: samuibrowser.com/from?url=dat...
Bernie Mulvey
Bernie Mulvey
Bernie Mulvey
The Transmitter
Louise Huuki-Myers
The ventromedial hypothalamus (VMH) and arcuate (ARC) nuclei of the hypothalamus play
critical roles in regulating metabolism and behavior. Here, Mulvey et al. create a
focused spatial transcriptomic ...
Boys and girls may be vulnerable to different genetic changes, which could help explain why the condition is more common in boys despite linked variants appearing more often in girls.
Objective: The objective of this study was to define the molecular neuroanatomy of the human habenula (Hb) and identify transcriptomic differences between brains of individuals with schizophrenia and ...
Got with the times + made a BSky to share our new, large-scale spatial RNAseq study of adult human #locuscoeruleus! Co-1st auth and cryostat wizard @heenadivecha.bsky.social squeezed 85 tissue sections into 43 Visium arrays. (1/8)
www.biorxiv.org/content/10.1...
9/8: The high-res spatial expression browser! Full-resolution of H&E stained tissue sections and the gene expression from them. Great for seeing neuromelanin. (One sample = one tissue section).
The locus coeruleus (LC) is a small noradrenergic nucleus in the dorsal pons that sends projections across the brain regulating sleep, arousal, attention, stress responses, and some forms of cognition...
Got with the times + made a BSky to share our new, large-scale spatial RNAseq study of adult human #locuscoeruleus! Co-1st auth and cryostat wizard @heenadivecha.bsky.social squeezed 85 tissue sections into 43 Visium arrays. (1/8)
www.biorxiv.org/content/10.1...
The locus coeruleus (LC) is a small noradrenergic nucleus in the dorsal pons that sends projections across the brain regulating sleep, arousal, attention, stress responses, and some forms of cognition...
