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Excited to share my postdoc work on the cryo‑EM structure of the budding yeast telomerase holoenzyme! 🧫🧬 It’s been a real privilege to be part of the awesome Kelly Lab @kellythd-nguyen.bsky.social. Grateful as well to the incredible facilities @mrclmb.ac.uk.
This project was a fantastic collaboration. Huge thanks to Hannah and Gabriela from the Wellinger and Chartrand labs for their incredible yeast genetics work, our summer student Tom Myles for early contributions, and our brilliant senior scientist Elsa Franco Echevarria's hard work during revision.
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Cryo–electron microscopy structure of the budding yeast telomerase holoenzyme
Telomerase is a reverse transcriptase that synthesizes telomeric repeats at chromosome ends, safeguarding genome integrity. We present the cryo–electron microscopy structure of the budding yeast telom...
www.science.org
Hongmiao Hu
Hongmiao Hu
Led by Investigator Scientist @hongmiaohu.bsky.social, @kellythd-nguyen.bsky.social’s group in the LMB’s Structural Studies Division have produced the first ever structure of telomerase from yeast. Read more here: mrclmb.ac.uk/news-events/... #LMBResearch #cryoEM 🧪
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MRC Laboratory of Molecular Biology