Lymph node metastasis is almost always synonymous with cancer progression, but in this fantastic study from @ubellackerlab.bsky.social, they reveal that it also imparts a key metabolic vulnerability: FSP1 dependency. Congrats Jess and @mariopalma.bsky.social!
Nathan Reticker-Flynn
Excited to share our work @nature.com! Postdoc @mariopalma.bsky.social, with major contributions from @retickerflynn.bsky.social and collaborators, discovered melanoma cells in lymph nodes gain a targetable FSP1 dependency that limits progression. #TeamFSP1
www.nature.com/articles/s41...