Newest preprint from our lab: a new family of promising synthetic CO2 fixation cycles that may outcompete the Calvin cycle and that Vittorio Rainaldi realized to a great extent in E. coli! Up to 11 heterologous enzymes in a cascade supporting CO2 fixation & growth! www.biorxiv.org/content/10.1...
Cool Preprint led by @mirbachh on comparing machine learning based engineering of a synthetic C1 fixation pathway vs the classic ALE based approach. ML allowed way faster pathway establishment and when combined with the evolved background improved growth by a factor of 3.🔥🎉
Our new paper is out: we present a quantitative framework to assess how (bio)tech interventions in plant agriculture could meaningfully contribute to climate mitigation. This may be the most important paper I ever publish #SyntheticBiology #ClimateAction #Agriculture #Biochar doi.org/10.1093/plph...
Looking for a #PhDposition in #PlantScience ?
Our #IMPRS @mpi-mp-potsdam.bsky.social and @unipotsdam.bsky.social is #hiring !
📅 Apply by 10 January 2026
More info:
👉 www.mpimp-golm.mpg.de/IMPRS-PhD
Please share this post to plant it in the right feed 🌱 #PlantSciJobs
Very excited to finally share my PhD paper, about advancing #chloroplast #synbio through high-throughput plastome engineering of #Chlamydomonas.
Huge thanks to the whole team!
www.nature.com/articles/s41...
Multi-lab, Multi-enzyme Study Demonstrates the Versatility of Bacterial Microcompartment Shells as a Modular Platform for Confined Biocatalysis https://www.biorxiv.org/content/10.64898/2026.03.18.712704v1
New preprint from our group! When we first started working with affordable, continuous-culture mini-bioreactors a few years ago, we realized they offered a unique solution for CRISPRi experiments, which rely on cell growth to dilute targeted proteins.
www.biorxiv.org/content/10.6...
Our work on #hornwort #pyrenoids is finally out in @science.org! 🎉 We uncovered how hornworts pack their Rubisco into pyrenoids and successfully recreated them in Arabidopsis. A key step toward engineering more efficient photosynthesis in crops @btiscience.bsky.social www.science.org/doi/10.1126/...
Please check out our improved #preprint:
CRISPR/Cas9 targeted genetic screening in Physcomitrella identifies novel cell division genes
Thank you, Elena Kozgunova for taking the lead.
#Physcomitrella #celldivision
www.biorxiv.org/content/10.1...
🔥🔥🔥 Friday Evening, Paper Out, Feierabend 🔥🔥🔥
When evolution and enzyme engineering team up, they can convince microbes to assimilate sustainable carbon substrates preparing them for a life in a circular bioeconomy.
doi.org/10.1016/j.ym...