Molecular biologist & geneticist Susan Lindquist (b. #OTD in 1949) was a pioneer in studying protein folding.
Her research demonstrated protein folding errors contribute heavily to neurodegenerative conditions like Alzheimer's & Parkinson's diseases. National Medal of Science in 2010. #WomenInSTEM
And risen star
1\ Excited to finally share some of my PhD work: OpenSplice!
We measured how >590,000 mutations affect exon inclusion across 600 human exons, creating a resource to study splicing regulation, benchmark variant effect predictors, and support variant interpretation.
Now published in NSMB!
Paper: doi.org/10.1038/s415...
Full PDF: rdcu.be/fhBtI
Overview of additions since the preprint👇 (1/5)
What if living cells compute in ways that silicon never can? Rather than mimicking computers, the future of biocomputation may lie in harnessing the unique information-processing strategies of evolution. Check this paper by @angelgm.eurosky.social and co. www.sciencedirect.com/science/arti....
Oh wow, the Venus flytrap closure mechanism 🤩🌱!
Looks like an awesome starting point for nature-inspired materials design ...
www.science.org/doi/10.1126/...
Accurate protein stability prediction for small domains using mega-scale experiments https://www.biorxiv.org/content/10.64898/2026.05.19.726285v1
📢📢 Job opening between the Bioinformatics Unit and my group (REPBIO) at @crg.eu
Interested in contributing to our efforts to leverage long-read sequencing technologies for human genome research?
Join us in Barcelona:
recruitment.crg.eu/content/jobs...
Please repost😊