1/ The past 36 hours have been significant for the ongoing #hantavirus outbreak. I still think the risk is low, but we're almost certainly going to see more cases. Here's what I'm watching:
1. Three new positive individuals (French, US, Spanish).
2. Four viral genomes.
3. Ship fully evacuated.
Global approaches to infectious disease surveillance and modelling are complex in a fragmented world.
We brought together an international team of researchers and policy makers to suggest a path forward using AI and federated/distributed frameworks.
www.nature.com/articles/s41...
Two more passengers (one in France and one in the US) from the MV Hondius testing positive after being evacuated yesterday. All data here: github.com/kraemer-lab/...
Moritz Kramer & colleagues discuss global approaches to infectious disease analysis and modelling, emphasizing federated approaches and addressing challenges in data interoperability, equity, & trust.
Part of our Focus issue on #infectiousdiseases.
Biosecurity depends critically on the early identification of novel pathogens.
Our international team developed a global multi-scale model of infectious diseases to evaluate the time to detection in aircraft wastewater vs. other surveillance modalities.
www.medrxiv.org/content/10.6...
First genome sequence from Andes hantavirus strain from ongoing ship outbreak posted on Virological: virological.org/t/complete-s... courtesy Swiss National Reference Centre for Emerging Viral Infections, Geneva University Hospitals, University of Zurich
Incredible work by Jonathan Pekar et al.: The emergence and molecular evolution of H5N1 influenza viruses in United States dairy cattle
www.biorxiv.org/content/10.6...
1/ Yesterday I was more worried about #hantavirus than I am today.
Why?
Flight attendant who was exposed - Tested negative
Viral genome - No concerning mutations
Two Singaporean's exposed - Tested negative
Data situation - We're tracking at Global.health (h/t @mugkraemer.bsky.social)
Joseph Tsui, Ben Reddy and I are recruiting a postdoc @psioxford.bsky.social to work on AI methods for multi-pathogen and multi-country biosurveillance optimisation for epidemic and endemic pathogens.
Closing date May 11th
my.corehr.com/pls/uoxrecru...
www.pnas.org/doi/10.1073/...