Happy to share our contribution to this new work led by @michalis-averof.bsky.social! @bekeloh.bsky.social and @metteh-thorsager.bsky.social tested membrane tags in the annelid Platynereis dumerilii — many reached the cell membrane, and several also label the developing nervous system in the larvae.
Huisken lab
Finding molecular tags that localise fluorescent proteins to the cell membrane was the goal of our latest paper, now published in Development @dev-journal.bsky.social. The tags act as address labels, sending proteins to the cell membrane, where they highlight the shape and arrangement of cells. 2/9
Summary: Screening a toolkit of diverse membrane-localising tags identifies candidates that efficiently localise proteins to the plasma membrane in a wide range of animals and choanoflagellates.
