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Online now: Ion sequential therapy aligned with pathological changes enhances cardiac function after myocardial infarction
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Zhong et al. map the spatiotemporal dynamics of zinc and copper following myocardial infarction. They develop a sequential Zn-Cu therapy, delivered via an epicardial device, that matches physiological needs. This targeted approach enhances cardiac repair and improves ventricular function by regulating the circadian gene PER2.
Ion sequential therapy aligned with pathological changes enhances cardiac function after myocardial infarction
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Cell Reports Medicine