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Congratulations to my first PhD student, Dr. Claire Chapman, on successfully defending her PhD! Stay tuned for an exciting story about the role of the small intestinal microbiota in susceptibility to cholera! #ProudPI
28d
Now published in Cell Reports! @cellpress.bsky.social www.cell.com/cell-reports... My postdoc Dr. Maria de la Paz Gutierrez led this work showing that cholera toxin drives epithelial L-lactate production in the small intestine, creating a nutrient that Vibrio cholerae exploits during disease
Important and timely read in the New England Journal of Medicine: Twelve former commissioners of the FDA express concern that the agency’s recent moves will undermine a regulatory model designed to ensure vaccine safety, effectiveness, and availability.
4d
6mo
What do I love the most about UCSD? My amazing colleagues. Congratulations @chulab.bsky.social and @alistairrussell.bsky.social on your promotion and to Kees Murre for being elected to the NAS!
Fabian Rivera-Chávez
Excited to share our new publication, out today in Nature! www.nature.com/articles/s41.... @kanchanj.bsky.social led this fascinating fungal-bacterial interaction project. We are grateful for our wonderful collaborators Brian Peters and David Underhill.
11mo
🌟 Applications are accepted for UC San Diego RAPID program's 2026-27 cohort. This highly-rated and effective #FacultyDevelopment opportunity is for junior faculty researchers in #InfectiousDiseases. 👉 Learn more and apply today at rapid.ucsd.edu. ⏰ Deadline: Sunday, March 1 #UCSD_RAPID
Fabian Rivera-Chávez
Gutierrez et al. show that cholera toxin induces epithelial LDHA-dependent L-lactate production in the small intestine, creating a nutrient niche that Vibrio cholerae exploits through LldD-mediated L-...
www.cell.com
Cholera-toxin-induced disease generates epithelial-cell-derived L-lactate that promotes Vibrio cholerae growth in the small intestine
Applications for UC San Diego RAPID program's 2026-27 cohort are now open! This highly-rated and effective career development opportunity is for junior faculty researchers in #InfectiousDiseases. Learn more and apply today at rapid.ucsd.edu! #UCSD_RAPID #FacultyDevelopment
9mo
ᐯIᑕTOᖇ ᑎIᘔET, ᗰᗪ
4mo
7mo
Manuela Raffatellu
Judith Behnsen
1/ Excited to share the first preprint from my lab! 🎉 My postdoc Paz asked how cholera toxin (CT) helps Vibrio cholerae thrive in the gut. Turns out, CT rewires epithelial metabolism toward L-lactate production—fueling pathogen growth in the small intestine during disease
Twelve former commissioners of the FDA express concern that the agency’s recent moves will undermine a regulatory model designed to ensure vaccine safety, effectiveness, and availability.
www.nejm.org
A Threat to Evidence-Based Vaccine Policy and Public Health Security at the FDA | NEJM
UCSD Health Sciences Office of Faculty Affairs
UCSD Health Sciences Office of Faculty Affairs
9mo
Commensal Candida albicans enhances the virulence and dissemination of Salmonella enterica subsp. enterica serovar Typhimurium.
www.nature.com
Commensal yeast promotes Salmonella Typhimurium virulence - Nature
Cholera toxin (CT) promotes Vibrio cholerae colonization by altering gut metabolism to favor pathogen growth. We have previously found that CT-induced disease leads to increased concentrations of L-la...
www.biorxiv.org
Cholera toxin-induced disease generates epithelial cell-derived L-lactate that promotes Vibrio cholerae growth in the small intestine
Fabian Rivera-Chávez