Fascinating new Perspective proposing that “epic dreams” may arise when REM sleep’s normal boundary between simulation and memory freaks down, with possible roles for orexin, MCH, and hippocampal gating. @alice-gregory.bsky.social @jakketamminen.bsky.social www.nature.com/articles/s42...
The MÖBIUS model proposes that REM sleep gating failures may mis-tag (pre)replay-like sequences as autobiographical memory, linking MCH-orexin balance, CA2 novelty tagging and θ-γ coupling to dream-re...