Developmental, stem cell and islet biologist, Professor for Beta Cell Biology @ Technical University Munich, Director of Institute for Diabetes and Regeneration Research @HelmholtzMunich
Heiko Lickert
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Congratulations Nike, Nicole, Kathy and the whole team to get this important study into the pipeline. If you womder if stem cell-derived islet compositions matters for safety and efficacy for the graft, our tissue engineering approach gives an answer. Check it out….
New resource online! 🐖 Benchmarking porcine #PancreaticDuctalOrganoids for #DrugScreening applications
by @ckarampelias.bsky.social, @heikolickert.bsky.social & colleagues @helmholtzmunich.bsky.social
🗞️ doi.org/10.1038/s443...
Check out the latest manuscript from the @heikolickert.bsky.social lab on generating a defined stem-cell derived islet product for transplantation.
A thorough characterization of the system particularly by our star PhD students Nike and Nicole! #PancSky
www.biorxiv.org/content/10.1...
It is my great pleasure to co-chair together with Leen‘t Hart the iPSC and islet organoids session tomorrow at the 10th Meeting of the Study Group on Genetics of Diabetes #SGGD2026 introducing great speakers: Charlotte Ling, Amna Khamis, and Heiko Lickert, @heikolickert.bsky.social
🔬 Breakthrough in Diabetes Research: An international team led by @heikolickert.bsky.social has published the first single-cell atlas comparing pancreas development across humans, pigs, and mice — marking a milestone in translational medicine.
@helmholtzmunich.bsky.social
t1p.de/dqwer
Comparing Pancreas Development Across Species to Advance Diabetes Research
New insights from international researchers led by #HelmholtzMunich & #DZD could reshape the future of #diabetes modeling & #RegenerativeMedicine.
👉 t1p.de/zg0ra
@diabresearch-dzd.bsky.social @heikolickert.bsky.social
Heiko Lickert
New from the @heikolickert.bsky.social clan and great work from Carina together with all collaborators and the Theis lab to study pancreas development across species, bringing new insights into conserved pathways using multimodal computational analysis www.nature.com/articles/s41... #PancSky
Happy to share a new tool from the @heikolickert.bsky.social lab!
We generated human iPSC fluorescent reporter lines to monitor Wnt/PCP signaling activity by Flattop in stem cell derived β-cells.
doi.org/10.1016/j.sc...
Thanks to all the co-authors that helped in the present and the past!
Obviously special shoutout to our great Proteomics and Genomics core facilities at @helmholtzmunich.bsky.social and of course the boss @heikolickert.bsky.social for his continuous support! Grateful to the @humboldt-foundation.de for supporting this work with a postdoctoral fellowship.
EMBO Molecular Medicine
Excited to see our review out in @cp-trendsendomet.bsky.social!
Great team effort and lots of fun to dive into how #islets form and how we can use this knowledge for #diabetes therapy.
@mireiamoli.bsky.social @ckarampelias.bsky.social @heikolickert.bsky.social
www.sciencedirect.com/science/arti...
Islets of Langerhans are highly structured mini-organs containing hormone-producing cells of the pancreas that regulate glucose metabolism. Studies of…
Check out the latest manuscript from the @heikolickert.bsky.social lab on generating a defined stem-cell derived islet product for transplantation.
A thorough characterization of the system particularly by our star PhD students Nike and Nicole! #PancSky
www.biorxiv.org/content/10.1...
Fully differentiated stem cell-derived islets (SC-islets) are proven to normalise blood glucose in type 1 diabetic patients. However, the presence of off-target cell types and the immature SC-islet fu...
Fully differentiated stem cell-derived islets (SC-islets) are proven to normalise blood glucose in type 1 diabetic patients. However, the presence of off-target cell types and the immature SC-islet fu...
This study establishes the pig as a complementary model for studying human pancreas development. It shows pigs mimic human developmental tempo, gene regulation, and endocrine cell emergence, offering ...
