Check out the latest manuscript from the @heikolickert.bsky.social lab on generating a defined stem-cell derived islet product for transplantation.
A thorough characterization of the system particularly by our star PhD students Nike and Nicole! #PancSky
www.biorxiv.org/content/10.1...
www.biorxiv.org
Fully differentiated stem cell-derived islets (SC-islets) are proven to normalise blood glucose in type 1 diabetic patients. However, the presence of off-target cell types and the immature SC-islet fu...