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In a large cohort of patients with ICB-treated glioblastoma, Catherine J. Wu & colleagues show that baseline mesenchymal transcriptional state predicts therapy response, and transition to non-mesenchymal state results in acquired resistance.
www.nature.com/articles/s43...
In a large cohort of participants with immune-checkpoint-blockade-treated glioblastoma, Ghannam et al. show that baseline mesenchymal transcriptional state predicts therapy response and transition to ...