It was a pleasure to work with @laylanassar.bsky.social to highlight this paper from @spencerfreeman.bsky.social and colleagues that shows how lysosomes can adapt in response to increased membrane tension
shawnferguson.bsky.social
@laylanassar.bsky.social & @shawnferguson.bsky.social @yaleschoolofmed.bsky.social discuss Kim et al.’s study in @jcb.org (doi.org/10.1083/jcb....) showing that TMEM63A protects #lysosomes from rupture by acting as a pressure relief valve when membrane tension rises. rupress.org/jcb/article/...
