We publish the scientific journals @jcb.org, @jem.org, @jgp.org, @jhumimmunity.org, and co-publish @lsajournal.org. Visit our journals at https://rupress.org
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In @jcb.org, @cytolabkoc.bsky.social show PCM1 multimerization scaffolds centriolar satellite assembly & drives stepwise client recruitment. Disrupting this homeostasis impairs ciliary signaling & mitosis. Key insights into how this membraneless organelle forms & remodels rupress.org/jcb/article/...
In contrast to prevailing dogma, Bhattacharyya et al. report that procollagen 1 assembles into a liquid condensate within cells, resolving the long-standing problem of how cells accommodate and export high concentrations of these bulky molecules from the ER. In @jcb.org: rupress.org/jcb/article/...
In @jem.org, Harms Pritchard, @marionpepper.bsky.social et al. dissect key CD4⁺ T cell/B cell interactions to define signals that govern the development of memory B cell populations. rupress.org/jem/article/...
#InfectiousDisease #HostDefense #LymphocyteBiology #BCells
🌐 Journal of Human Immunity (JHI) @jhumimmunity.org is now officially indexed in #PubMed Central and PubMed. This includes all future papers and the complete back catalog dating back to our first issue. Read the full announcement and explore the journal here: rupress.org/jhi/pages/pm...
Publishing in @jcb.org, @jem.org, @jgp.org, @jhumimmunity.org, and @LSAJournal.org enables authors funded by National Institutes of Health (NIH), Howard Hughes Medical Institute (HHMI), and other funders an easy pathway to compliance. Learn more:
👉 rupress.org/pages/nih-hh...
In @jem.org, Ward, Kar, Balan, and Bhardwaj @bhardwajlab.bsky.social review how conventional type 1 #DendriticCells (cDC1s) coordinate antitumor immunity through cross-presentation, immune cell networking, and spatial organization in tumors. rupress.org/jem/article/...
#CancerFocus #Immunotherapy
In @jhumimmunity.org, Mehmet Cihangir Catak, Bernice Lo, Safa Baris et al. describe the first case of homozygous #CTLA4 deficiency, which drives severe early-onset #autoimmunity through profound T and B cell dysregulation. rupress.org/jhi/article/...
#ClinicalPhenotypes #Diagnostics #Therapeutics
New review @jgp.org: Shimon Schuldiner recounts the decades-long journey of VMAT research, bridging foundational bioenergetics with recent high-resolution structural breakthroughs. rupress.org/jgp/article/...
#Neuroscience
News & Views @jhumimmunity.org: A new report in JHI from Catak et al. (rupress.org/jhi/article/...) deepens our understanding of human disease associated with loss of #CTLA4. Helen C. Su @niaidnews.bsky.social discusses the findings: rupress.org/jhi/article/...
Spotlight @jcb.org: Nicola Diny @unibonn.bsky.social previews a study from @petrovalab.bsky.social et al. (rupress.org/jcb/article/...) which reveals that #eosinophils drive a developmental program for postnatal intestinal remodeling and maturation. rupress.org/jcb/article/...
#Development
Rockefeller University Press
Rockefeller University Press
Rockefeller University Press
Rockefeller University Press
Rockefeller University Press
Rockefeller University Press
Rockefeller University Press
Rockefeller University Press
Rockefeller University Press
Rockefeller University Press
Video
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Catak et al. describe the first case of homozygous CTLA-4 deficiency, which drives severe early-onset autoimmunity through profound T and B cell dysregulat