New publication for SLC13A5 targeting compounds! Discovery of the BI chemical probe is out now in J. Med. Chem.
Great work by Andrew Quigley, Liz Carpenter, and colleagues from Oxford's @cmd.ox.ac.uk, @boehringerglobal.bsky.social, and @thesgc.bsky.social
pubs.acs.org/doi/10.1021/...
Citrate is a key metabolic intermediate that regulates both glycolysis and lipid metabolism. While most citrate is produced in mitochondria, some is imported from the bloodstream by the SLC13 family o...