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Accurate RNA structure prediction remains a challenge, despite recent computational advances. This study presents DRFold2, a #DeepLearning framework that significantly enhances accuracy of de novo #RNAstructure prediction by increasing contact prediction precision @plosbiology.org πŸ§ͺ plos.io/4aoOQiX
Finally had the time to look through and process more photos I’ve taken in Senegal. Here’s some of my favourites!
Also extremely happy to see work finally published! Kudos to @yushuchen.bsky.social's tenacity and hard work! Read our previous thread and the paper itself for details/updates! Happy to chat if you find our findings interesting! #MicroSky www.pnas.org/doi/10.1073/...
3mo
3mo
3mo
www.pnas.org
Mycolic acids (MAs) are the major component of the mycobacterial outer membrane, a key contributor to the intrinsic resistance of mycobacteria to e...
Exquisite specificity of Pks13 defines the essentiality of trehalose in mycobacteria | PNAS
Shu-Sin Chng
PLOS Biology
Cornelius Lee
Happy to share our newest preprint addressing the basis of trehalose essentiality in mycobacteria! This is a story brewing in the lab for the longest time, started by MSc grad Justin Lim, & now completed by the amazing PhD grad-turned-postdoc @yushuchen.bsky.social! #MicroSky #Mycobacteria 1/8
Apr 10, 2025
2mo
Here is it! Super new science from us on horizontal gene transfer & bact defense systems! Liyana OW YONG discovered the first-of-its-kind defense factor AbjA that triggers 'abortive conjugation' as a defense mechanism, by targeting the T4SS! How neat?! #MicroSky 1/7 www.biorxiv.org/content/10.6...
🚨New Influenza Tool🚨 Interested in IAV mutations? Looking for markers of mammalian adaptation? Frustrated by converting between IAV numbering systems? The #Flu-MutationExplorer, a new tool from @cvrbioinfo.bsky.social and @royalvetcollege.bsky.social, is here to help: flu-gdb.cvr.gla.ac.uk (1/n)
Shu-Sin Chng
3mo
Shu-Sin Chng
www.biorxiv.org
Exquisite specificity of Pks13 defines the essentiality of trehalose in mycobacteria https://www.biorxiv.org/content/10.1101/2025.04.03.647003v1