DPhil student working on influenza in Kapanidis and Fodor lab at University of Oxford. Previously in Vignuzzi lab. A*STAR National Science Scholar. Photojournalism enthusiast.
Cornelius Lee
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Finally had the time to look through and process more photos I’ve taken in Senegal. Here’s some of my favourites!
Cornelius Lee
We're still not over Monday's Artemis II Moon fly-by 🌑 The crew should splash down tomorrow. Here are some of our favourites of the breath-taking images from the mission so far
You can check out our live blog from the history fly-by, as it happened: www.nature.com/articles/d41...
📸 NASA
Accurate RNA structure prediction remains a challenge, despite recent computational advances. This study presents DRFold2, a #DeepLearning framework that significantly enhances accuracy of de novo #RNAstructure prediction by increasing contact prediction precision @plosbiology.org 🧪 plos.io/4aoOQiX
Now online! Giant DNA viruses encode a hallmark translation initiation complex of eukaryotic life
🚨New Influenza Tool🚨
Interested in IAV mutations?
Looking for markers of mammalian adaptation?
Frustrated by converting between IAV numbering systems?
The #Flu-MutationExplorer, a new tool from @cvrbioinfo.bsky.social and @royalvetcollege.bsky.social, is here to help:
flu-gdb.cvr.gla.ac.uk
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Nature
How could a simple self-replicating system emerge at the origins of life? RNA polymerase ribozymes can replicate RNA, but existing ones are so large that their self-replication seems impossible. Could they be smaller?
Excited to share our latest work in @science.org on a new small polymerase.
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Also extremely happy to see work finally published! Kudos to @yushuchen.bsky.social's tenacity and hard work! Read our previous thread and the paper itself for details/updates! Happy to chat if you find our findings interesting! #MicroSky
www.pnas.org/doi/10.1073/...
Transient RNA structures play a key role in the emergence of highly pathogenic avian influenza viruses! Great to see this collaboration with Mathis Funk, Mathilde Richard, Stephen Cusack, and others in @science.org www.science.org/doi/10.1126/...
Here is it! Super new science from us on horizontal gene transfer & bact defense systems! Liyana OW YONG discovered the first-of-its-kind defense factor AbjA that triggers 'abortive conjugation' as a defense mechanism, by targeting the T4SS! How neat?! #MicroSky 1/7
www.biorxiv.org/content/10.6...
The Social Lives of Viruses is coming to Vancouver, Canada, from 4th-8th August 2026!
This is a free meeting dedicated to all aspects of virus-virus interactions & evolution.
To apply: socialviruses.zoology.ubc.ca
@sociovirology.bsky.social #socialviruses #evosky #lovevirology #virosky
The emergence of a chemical system capable of self-replication and evolution is a critical event in the origin of life. RNA polymerase ribozymes can replicate RNA, but their large size and structural ...
Highly pathogenic avian influenza viruses (HPAIVs) derive from H5 and H7 low pathogenic avian influenza viruses (LPAIVs). Although insertion of a furin-cleavable multibasic cleavage site (MBCS) in the...
Extremely proud of newly minted PhD Dr Nur Liyana bte Ayub Ow Yong for her work in our lab! Some new science coming soon so stay tuned! 🎉🎉
Shu-Sin Chng
Giant DNA viruses encode a cap-binding complex homologous to eIF4F, the defining translation-initiation complex of eukaryotes. The viral cap-binding complex is required for viral protein synthesis and enables an unusual degree of replication plasticity under altered host conditions.
Happy to share our newest preprint addressing the basis of trehalose essentiality in mycobacteria! This is a story brewing in the lab for the longest time, started by MSc grad Justin Lim, & now completed by the amazing PhD grad-turned-postdoc @yushuchen.bsky.social! #MicroSky #Mycobacteria 1/8
Shu-Sin Chng
Exquisite specificity of Pks13 defines the essentiality of trehalose in mycobacteria https://www.biorxiv.org/content/10.1101/2025.04.03.647003v1
