Columbia PhD candidate studying viral RNA structure and degradation
Jeanine Gezelle
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If you want to know what 3′UTRs with long conserved sequence stretches do, check out our BioRxiv preprint doi.org/10.64898/202....
They form functional intermolecular 3′UTR-3′UTR interactions that enable co-folding of proteins to rapidly induce transcriptional programs.
Some molecular machines, like ribosomes, can persist for long periods of time in cells.
Could molecular aging of ribosomes shape how proteins are made?
In our new preprint we track ribosomes as they age in cells and uncover unexpected effects on translation (1/10)
www.biorxiv.org/content/10.6...
Rob Reiner made “the kinds of films that accompany people throughout their lives,” Alexandra Schwartz writes. “They are comfort watches in the best sense.” newyorkermag.visitlink.me/jCHRSD
Christine Mayr
Jordy F. Botello
Mamdani: "New York will remain a city of immigrants, a city built by immigrants, powered by immigrants, and as of tonight, led by an immigrant."
🔬 #Trypanosomes process their large rRNA in a highly unusual way-by cutting it into six pieces. A new study from @schneian.bsky.social lab identified two essential proteins, TbLrRP1 and TbLrRP2, that drive this process. Read more: doi.org/10.1093/nar/...
#NARBreakthrough #RibosomeBiogenesis
The New Yorker
(1/7) How does T. brucei achieve a 140-fold stoichiometric excess of VSG mRNA over upstream ESAGs from a single polycistronic unit?
Our latest research in @natmicrobiol.nature.com reveals a mechanism of spatially regulated RNA decay to fine-tune expression of virulence genes
Excited to share our latest work!
The oncogenic m5C writer NSUN2 achieves substrate specificity by recognizing RNA structure and conformational dynamics. RNA folding shapes methylation! Congratulations to the team! Thank you, colleagues and supporters! ttps://nature.com/articles/s41586-026-10582-9
Aaron Rupar
Preprint on the Stanford #RNA 3D folding Kaggle challenge is out. My scientific new year’s resolution is to brush up on template-based modeling. #gofai
www.biorxiv.org/content/10.6...
1/9 New preprint from the Sternberg Lab in collaboration with the Nishimasu Lab! We uncover how the DRT3 antiphage immune system pairs two reverse transcriptases, one RNA-templated and one protein-templated, to build a double-stranded DNA effector. doi.org/10.64898/202...
Nucleic Acids Research
NSUN2 is an enzyme that adds a small chemical mark to RNA molecules and uniquely selects its targets based on specific sequence patterns and structural features.
Automatically predicting RNA 3D structure from sequence remains an unsolved challenge in biology and biotechnology. Here, we describe a Kaggle code competition engaging over 1700 teams and 43 previous...
With many postdoc grants like the NSF PRFB, Ford Fellowship, and Hanna H. Gray fellowships disappearing, I am currently looking for grants that could fund incoming postdoctoral scholars. Here is a thread of some of them 🧵
