Phage receptor-binding proteins are known for their LEGO-like modularity, but we still do not fully understand their evolutionary potential and how it shapes phage host range. Our new preprint examines this systematically in Klebsiella phages. 🔗 www.biorxiv.org/content/10.6...
Thread 🧵
Cheap and easy method for nanopore sequencing phage DNA directly from plaques.
Proud of lab members Brenna and Patrick for doing this work *with absolutely no help from me* !!
www.nature.com/articles/s41...
OGG1-Binding to Oxidized Guanine Base in Viral DNA Overcomes Epstein-Barr Virus Latency https://www.biorxiv.org/content/10.64898/2026.06.05.728896v1
Our paper is out in Nature Microbiology: functional analysis of 80 phage sponges, revealing new sponges that inhibit bac immunity by binding the immune signals cCMP, cUMP and N7-cADPR
Thanks to all coauthors and our collaborators at the Kranzusch Lab. Congrats Romi!
www.nature.com/articles/s41...
CapK is a bacterial DNA damage-activated kinase that phosphorylates transcriptional repressor CapS to control adjacently-encoded anti-phage immune pathway genes in response to a universal stress signal, DNA damage
@kevincorbett.bsky.social and colleagues
link.springer.com/article/10.1...
Balancing of immune activation and suppression during phage infection https://www.biorxiv.org/content/10.64898/2026.06.04.730250v1