Turns out - we see the same pattern, bursting for some twitches but inhibition for others. What's super cool is that it's sped up. The burst and the inhibition is only ~25% as long as during wake, so it's like the whole motor system is accelerated. So what kind of twitches happen during the bursts?
Jimmy Dooley
Same basic story for the P24 M1-RN data (Fig. S4) - there's a huge discrepancy between EMG and movement during wake, but for twitches, the correspondence is pretty good.
I keep going back to how tough it would be to explain REM sleep and twitching to an alien (assuming they don't do it too, which maybe isn't a given)
Thanks to everyone in the lab for getting this out the door. And we've got way cooler M1-RN stuff in the works - so stay tuned!
