#AACR2026 kicks off this weekend! Come find me at my posters!
🧪 Constitutive NRF2 activation drives excess cysteine stress
🗓️ April 19th, 2-5pm
📍Section 22, Board 3
🧪 Cysteine as a driver of resistance to Bortezomib
🗓️ April 20th, 9am-12pm
📍Section 16, Board 8
Just landed in Cincinnati for the first annual Future Faculty Conference hosted by the University of Cincinnati Cancer Center. Grateful for the invitation to grow my network, attend workshops for professional development, and meet with potential mentors and collaborators!
Check out our latest work out today in @natmetabolism.nature.com in which we describe a new metabotype (metabolic phenotype): excess cysteine stress. We discovered novel cysteine conjugates and show how pyruvate modulates free intracellular cysteine levels. Grateful for an awesome team!!
Jen Brain (Crainic)
Overjoyed to have the opportunity to present my work orally at the Cancer Metabolism Showcase! Hope to see you there virtually!
Come chat with me at #AACR2026 @theaacr.bsky.social about this work or our next story! Excess cysteine stress: Poster #537 4/19 2-5pm Section 22, Board #3; Cysteine as a driver of resistance to Bortezomib: Poster #1788 4/20 9am-12pm, Section 16, Board #8.
Jen Brain (Crainic)
ATTENTION: NSF GRANT RECIPIENTS
We received a heads up from a trusted source that you should proactively download/print/screen shot any documentation on research.gov pertaining to your NSF awards, both those that are current and any that have closed in the last 5-6 years.
1/n
Jen Brain (Crainic)
Pleased to share our recent work out today in @natmetabolism.nature.com. This study addresses a longstanding mystery - NRF2-driven cancers increase cysteine acquisition (via xCT) by ~5x - so where does all that cysteine go?
That's a wrap on #AACR26! Researchers from Fred Hutch and @uwmedicine.bsky.social were in San Diego at @theaacr.bsky.social Annual Meeting sharing findings in cancer prevention, diagnosis and care — from new insights on #colorectalcancer risk to emerging targets for #ovariancancer and more.
Jen Brain (Crainic)
Also, check out this great N&V write up from the PapaG lab: www.nature.com/articles/s42...
