Sad to hear of the passing of Robert Ricklefs - a giant of Ecology who simultaneously pushed forward big ideas at multiple biological levels yet took time for detailed natural history .. McGill does a nice job summarizing his impressive contributions 🌐🧪 dynamicecology.wordpress.com/2026/06/11/r...
New preprint from my PhD is out!
We show that loss of miR‑219 disrupts neural border gene programs and prevents neural crest specification.
Excited to finally share it 🚀
www.biorxiv.org/content/10.6...
#xenopus #miRNA #genomics
Robert Ricklefs, a giant of ecology, passed away on Sunday. It is hard to overstate the extensive impact Bob had on the field. He was elected a member of the National Academy of Sciences in the US,…
dynamicecology.wordpress.com
www.biorxiv.org
Neural crest (NC) multipotent stem cells give rise to many tissues including most of the peripheral nervous system, pigment cells and the craniofacial mesenchyme and skeleton. During gastrulation and ...
Book review 📚 How long can humans live? We simply don’t know
go.nature.com/3QelWur
An antagonistically pleiotropic gene regulates vertebrate growth, maturity, and lifespan
Great first post by @itamarh.bsky.social 😀
Very happy to contribute to this cool study!
Job advert!
There is microbiology lectureship at @biouea.bsky.social with a focus on non-academic impact:
vacancies.uea.ac.uk/vacancies/20...
🚀 The new edition of Beyond Beginner R course is now underway. A few improvements this time:
- @philipleftwich.bsky.social & @eivimeycook.bsky.social l as instructors
-More R reproducibility examples
- Quarto workflows
- Handling large datasets
- Integration of AI tools
shorturl.at/R97jw
go.nature.com
Claims about the upper limits to human lifespan are characterized by hype, deficient data and shoddy science, says longevity researcher Saul Newman.
View details and apply for this Impact Lecturer in Microbiology (ATR1737) vacancy in University of East Anglia. Faculty of Science
School of Biological Sciences
Impact Lecturer in Microbiology...
"Unlike my good friends Dobzhansky and Simpson, I did not think that the only role I could take in a society was that of president."
Ernst Mayr on why he became the first editor of Evolution.
Longer human lives may be making an old evolutionary pattern harder to ignore. Late-acting harmful variants and youth-tuned pathways can now shape health on a scale selection never removed. doi.org/hb7fmz
And the press release is at www.su.se/english/news...
We took ~750,000 whole genomes and found the putative mechanism by which mitochondrial DNA mutations accumulate with age in blood. Spoiler: we think these mutations arise by replication error and tag age-related clonal hematopoiesis. Read @nature.com broad.io/ob2jft
phys.org
A review article now published in Nature Reviews Genetics brings together evolutionary theory, comparative genomics and large-scale human genetics to explain why we age and why aging rates differ among individuals and species.
Genome-wide analyses indicate that accumulation of mitochondrial DNA mutations, a hallmark of ageing, may be caused by cryptic replication errors, which act as passenger mutations that eventually become detectable with age owing to age-related somatic mosaicism, rather than oxidative damage.
1/6) What if aging begins, in part, as a bargain made in youth? In turquoise killifish, editing vgll3—a gene linked to puberty-timing in humans and salmon—revealed one of the first causal single-gene examples of antagonistic pleiotropy in vertebrate aging 🧵
Science X / Phys.org
Arvid Ågren
Judith Mank
Rahul Gupta
Itamar Harel
It turns out all that screen time disrupts brain development...in guppies. Now out @royalsocietypublishing.org royalsocietypublishing.org/rsbl/article....
