I wrote a paper with @lorenzlamm.bsky.social, @marionjasnin.bsky.social, @tingyingpeng.bsky.social, F. Eckardt and B. Schworm and got accepted at #NeurIPS2025 and fun fact: 90% of viewers are enby vegans! 🤟
So if u fit there, u might wanna check it out! Maybe also if you don't. We're allies here <3
Online Now: Toward community-driven visual proteomics with large-scale cryo-electron tomography of Chlamydomonas reinhardtii Online now:
In case you're missing my poster at #NeurIPS2025 about how I fine-tuned DINOv2 to ophthalmological images, here are some animations so you don't miss out!
🔗 Preprint: doi.org/10.48550/arX...
🔗 Code: github.com/peng-lab/rmlp
🧵1/9
Are you also often frustrated when DINOv2 puts very high attention on background patches, rather than cute fox heads?
@virtualhomo.bsky.social found an elegant way to regularize DINOv2 training using randomised linear algebra 🤯
Check out his thread or even his poster if you're at #NeurIPS2025.
Long in the making, but happy to present the Chlamydomonas chlororibosome!
Cryo-ET🔬reveals a large new domain on the small subunit, built from multiple extensions in conserved ribosomal proteins.
bioRxiv 📖: shorturl.at/q44tG
This suggests greater chlororibosome diversity than expected!
1/n 🧵
This one was quite the journey! The paper describing the #ChlamyDataset is finally out and on the cover of Mol Cell!
This beautiful rendering made by co-author @jessheebner.bsky.social and Holly Peterson shows an instance of mitochondrial fission found in the dataset 😍
[Maybe long thread ahead]
How does molecular valency shape condensate assembly and function? We used the CO2-fixing organelle in algae—the pyrenoid—to find out… 🧵
Preprint here!:
www.biorxiv.org/content/10.6...
@cellarchlab.com @phaips.vd.st @biologyatyork.bsky.social
#Rubisco #PhaseSeparation #Condensates #Pyrenoid
The #ChlamyDataset is on the cover of @cp-molcell.bsky.social 🖼️🥰!
Read @lifeonthewedge.bsky.social's great thread🧵 for the inside scoop🍨 on all the #TeamTomo developments already made possible since these 1829 tomos hit EMPIAR 🧪 🧶🧬
For more, here's the old preprint thread:
bsky.app/profile/cell...
Molecular Cell
We're super excited to share MissAlignment: a new ML-based approach to reference-free tilt series alignment, spearheaded by @martenchaillet.bsky.social. We think it's going to make your cryo-ET life a lot better.
Preprint: www.biorxiv.org/content/10.6...
Code: github.com/warpem/miss-...
🧶 Thread:
Video
Joel Valdivia Ortega
Joel Valdivia Ortega
James Barrett
Florent Waltz
Lorenz Lamm
Excited to share our paper about copick, a dataset API and toolkit for collaborative annotation and analysis of #cryoET data! Whether you're picking particles or curating segmentations, copick reduces friction and brings #OME-Zarr to cryoET without breaking pipelines.
🧵👇
doi.org/10.1002/pro.70578
Ricardo D. Righetto
Ben Engel
Dimitry Tegunov
Utz Ermel
Video
Vision Transformers (ViTs), such as DINOv2, achieve strong performance across domains but often repurpose low-informative patch tokens in ways that reduce the interpretability of attention and feature...
Using the latest advances in instrumentation and computational workflows, Kelley et
al. present a large-scale annotated cryo-electron tomography dataset of the model
green alga, Chlamydomonas reinhard...
Using the latest advances in instrumentation and computational workflows, Kelley et al. present a large-scale annotated cryo-electron tomography dataset of the model green alga, Chlamydomonas reinhardtii. This unprecedented community resource is rich in high-resolution biological information and empowers the development of new methods for visual proteomics.
dlvr.it
This one was quite the journey! The paper describing the #ChlamyDataset is finally out and on the cover of Mol Cell!
This beautiful rendering made by co-author @jessheebner.bsky.social and Holly Peterson shows an instance of mitochondrial fission found in the dataset 😍
[Maybe long thread ahead]
In case you're missing my poster at #NeurIPS2025 about how I fine-tuned DINOv2 to ophthalmological images, here are some animations so you don't miss out!
🔗 Preprint: doi.org/10.48550/arX...
🔗 Code: github.com/peng-lab/rmlp
🧵1/9
Using the latest advances in instrumentation and computational workflows, Kelley et
al. present a large-scale annotated cryo-electron tomography dataset of the model
green alga, Chlamydomonas reinhard...
