Computational structural biologist. Gay, out & proud since 1986. I support transgender & nonbinary people. Living with CLL/SLL. Video about my LGBTQ+ life in science: https://tinyurl.com/45srzjdw. Views my own, not my employer's.
Roland Dunbrack 🏳️🌈
Loading...
Medical treatment, an allegory...
Doctor: "the test results are back, I'm afraid your child has cancer"
Parent: "OMG. Is it treatable."
Doctor: "yes... But we don't do that."
Parent: "what do you mean? Is the treatment awful, or ineffective?"
Doctor: "... No..."
White House reclassifies federal epidemiologists and other scientists from civil servants to ‘at-will’ hires
www.scientificamerican.com/article/whit...
STOP using ipTM for #AlphaFold PPI screens.
* Artificially LOW when both full-length proteins have irrelevant, non-binding IDRs/domains.
* If one protein is folded & other contains irrelevant IDRs or domains, the score is too HIGH bc of d0.
* Use ipSAE or LIS.
www.biorxiv.org/content/10.1...
