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CPMDS Research Highlight 🔬 (Drs. Igor Vorobyov, Vladimir Yarov Yarovoy, Colleen E. Clancy) Researchers used advanced simulations to reveal how ligands dissociate from membrane receptors, uncovering hidden molecular pathways that could improve drug discovery and precision therapeutics. 💻
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Read more here: elifesciences.org/reviewed-pre...
CPMDS Research Highlight 🔬 CATVariant is a new open-access webserver for studying genetic variants, integrating population, clinical, structural, and literature data with computational predictors to help interpret variant effects. Read more: doi.org/10.1093/nar/... | Explore: catvariant.com
🔬 CPMDS Research Highlight (Dr. Pei-Chi Yang) New eLife research introduces AI-powered “digital twins” of heart cells, using synthetic data and electrophysiology to predict cell-specific behavior. This work could advance precision medicine, drug safety testing, and arrhythmia research.
🔬CPMDS Research Spotlight New research highlights how advances in cardiovascular ion channel and Ca²⁺ signaling research are shaping future therapies for heart disease, including arrhythmias and heart failure. ❤️🫀 Read more: pubmed.ncbi.nlm.nih.gov/41605640/
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New research shows how AlphaFold can predict hERG ion channel states, improving drug safety screening and helping identify arrhythmia risks earlier in drug development. A major step toward safer, AI-driven therapeutics. #AI #DrugDiscovery Read more here: pmc.ncbi.nlm.nih.gov/articles/PMC...
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🔬 CPMDS Research Highlight New research highlights how AI and digital health technologies are improving healthcare quality and patient safety through proactive, data-driven care, clinical decision support, telehealth, and better care coordination. #DigitalHealth pubmed.ncbi.nlm.nih.gov/40752934/
CPMDS Research Highlight 🔬 Computational models reveal how the autonomic nervous system regulates blood flow and blood pressure across molecular, cellular, and tissue scales, providing insights that could guide future precision cardiovascular therapies.
Read more: pubmed.ncbi.nlm.nih.gov/41083200/
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The regulation of vascular tone underlies normal cardiovascular homeostasis, ensuring appropriate distribution of blood flow to tissues and maintenance of blood pressure. Computational modeling and si...
journals.physiology.org
Smooth signals: computational insights into autonomic vascular control | American Journal of Physiology-Cell Physiology | American Physiological Society