PI at the University of Zürich. Natural Products Discovery, Metabolomics, Bacteria Metabolites, Cyanobacteria Blooms, Quorum Sensing, Chemoselective Probes, Diazeniumdiolates. https://www.simonsiebergroup.com/
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Our highlight review on recently isolated cyanobacterial metabolites is out @natprodreports.rsc.org !🥳 Covers isolation, structure elucidation (analytical techniques, biosynthesis and total synthesis). Great work with @elisabethjanssen.bsky.social!
@chem.uzh.ch
pubs.rsc.org/en/content/a...
Into natural product biosynthesis & tailoring enzymes? Frustrated by the lack of a dedicated resource to explore their functions? Tired of endless literature searches for reaction info? Meet the MITE database, freely available at mite.bioinformatics.nl. Preprint: doi.org/10.26434/che... (1/8)
We are looking for a 3-year postdoc to work with Daniel Probst, Justin van der Hooft and myself on an exciting project involving federated learning and integrative omics for discovery of new antibiotics from natural products.
Apply here: www.wur.nl/en/vacancy/p...
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Thrilled to see our study on novel toxins from cyanobacteria blooms in #Fribourg in STOTEN! Our results indicate that Phormidium is the producer of cyanopeptolins, whose side chains are crucial for their activity.
Great collaboration with Pilar Junier
www.sciencedirect.com/science/arti...
We built GenoPHI: a machine learning workflow that predicts phage-host interactions at strain level. This could help rapidly select phages to treat drug-resistant bacterial infections or for microbiome engineering without exhaustive lab testing.
www.biorxiv.org/content/10.1...
🔓Take a look at this #OpenAccess review from @simonsieber.bsky.social & @elisabethjanssen.bsky.social in our latest issue highlighting the cyanobacterial metabolites reported between 2021–2024 #natprod #secmet
📍 @chem.uzh.ch, @eawag.bsky.social
