How do cells break symmetry to generate new shape and form? Using the apical hook as a model, we @joeecker.bsky.social applied spatial and single-cell multiomics, and identify a regulatory hotspot in a transient cell niche that drives this U-shaped structure 1/8
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Travis Lee
Transient cell states encode positional information to direct asymmetric growth https://www.biorxiv.org/content/10.64898/2026.05.21.726925v1