1/ New paper out in Nature Communications!
We studied the salivary amylase gene, AMY1, in Indigenous Andean populations and found evidence that high AMY1 copy number rapidly increased in frequency, likely through recent positive selection.
doi.org/10.1038/s414...
Individuals are modelled as mixtures of (ghost) ancestors and we simultaneously infer their local ancestry contributions. Additionally, we propose looking at "types of mutations" in each of the ancestry segments, which is not used in GhostBuster, to provide independent evidence for these events.
Our preprint is now out, looking at genomic history and selection in Britain, with a focus on the Roman and early medieval periods. Comments welcome!
www.biorxiv.org/content/10.6...
@boothicus.bsky.social @leospeidel.bsky.social @pontus-skoglund.bsky.social
New ad for an independent postdoc in mathematics/statistics/machine learning for Biology in my institute at RIKEN (not my lab), ranging from 3 to 7 years. Our institute is entirely English-run, and a good mix of expertise on maths/physics/stats/bio! www.riken.jp/en/careers/r...
Postdoc position in my group in Tokyo!
Please get in touch if you are interested.
And happy to discuss projects - these would range from developing new methods to analysis of new genomes that we are now sequencing in the lab.
Job Ad: www.riken.jp/en/careers/r...
Lab page: speidellab.github.io