The tau protein might be the most complex and fascinating amyloid forming protein.
It is particularly complicated to make tau amyloid in vitro.
In this perspective, we discuss the current challenges to make tau amyloids that are relevant to tauopathies.
febs.onlinelibrary.wiley.com/doi/full/10....
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients af....