My second-to-last PhD paper is out in JOC, and it's one of my favorites!
We looked at how flexible tether composition affects bifunctional catalysis. 🧵 #Chemsky #Catalysis
doi.org/10.1021/acs....
doi.org
The crossed aldol condensation between hydrocinnamaldehyde and 2,6-dimethoxybenzaldehyde was used to explore bifunctional catalysis by a set of diamines. The catalytic mechanism appears to involve nuc...