DNMT1 inhibition reprograms T cells to NK-like cells with potent antitumor activity www.science.org/doi/10.1126...
☕Have you read this study from our journal (@naturecellbiology.bsky.social) yet?
Studies of endolysosomes and #proteostasis suggest a role for lysosomal quality control in #Alzheimers disease pathology.
bit.ly/4lSORPV
We have an active search for tenure-track faculty interested in #ImmuneEngineering #ProteinEngineering #GenomeEngineering & #CancerImmunology. Join the newly formed Center for Cellular Therapies and Cancer Immunology #CCTCI. Learn more at apply.interfolio.com/173562. #facultyjobs
Good news keeps coming! Excited to share our latest preprint expanding myeloid cell editing capabilities: Virus-like particles enable targeted gene engineering and pooled CRISPR screening in primary human myeloid cells, led by Hyuncheol Jung and Pascal Devant joint with @juliacarnevale.bsky.social
Wow!!! 👏👏👏 Amazing to see this develop over the years!
www.nytimes.com/2025/06/20/h...
Ohio Medicaid got rid of big middlemen. Says it paid pharmacies a lot more — and saved $140M ohiocapitaljournal.com/2025/04/17/o...
Thanks to Dr. Syal & @nbcnews.com for visiting our #CARTcell program to highlight one of our courageous little patients with #DIPG #DMG. So much work left to do but thankful for the support of Seattle Children’s and our brave families. ❤️
www.nbcnews.com/now/video/ex...
Ming Tommy Tang
Stylianos Lefkopoulos (he/him)
Jaehyuk Choi
some GD T cell lymphomas are addicted to JAK-STAT signaling and relapse with new JAK-STAT mutations, much like melanomas to BRAF inhibitors. ? new approach ? to treating these aggressive diseases. cell of origin (GD cells) important but unclear why. stay tuned for more.
www.jci.org/articles/vie...
Cas12a-knock-in mice for multiplexed genome editing, disease modelling and immune-cell engineering
www.nature.com/articles/s41...
Review @jimmunol.bsky.social
Can autoimmune disease be cured by deep CD19+ cell depletion?
doi.org/10.1093/jimm...
Marson Lab
Chou et al. generate transdifferentiated human neurons from fibroblasts from young or aged individuals and patients with Alzheimer’s disease. Studies of endolysosomes and proteostasis suggest a role f...
The Ohio Department of Medicaid department in 2022 gave powerful prescription drug middlemen the boot and created a new system. The result: Fees paid to pharmacies were boosted more than 1,200% while ...
