We discussed in our past journal club how Benztropine, a Parkinson’s drug, limits intracellular mycobacterium tuberculosis growth by modulating host histamine receptor H1, highlighting histamine signalling as a host-directed target.
www.nature.com/articles/s44...
npj Antimicrobials and Resistance - The Parkinson’s drug benztropine possesses histamine receptor 1-dependent host-directed antimicrobial activity against Mycobacterium tuberculosis
