Systems Pharmacology and Biology Lab at @DepBiomedicine, University of Basel, Switzerland.
We exploit metabolic weaknesses for therapeutic applications.
www.zampierilab.org
Zampieri Lab
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Welcome, Kevin Ritter, as a new PostDoc in our lab!
He will be working on establishing in vitro frameworks to study metabolic reactions in defined biological extracts. With his background in organic chemistry, he will also reinforce our analytical expertise and help us set up our LC/MS workflow.
In today's journal club, we discussed a recent contribution from Michael Zimmermann's group @embl.org, Heidelberg, available on bioRxiv.
Neat work illustrating the potential of individual members of the gut microbiome in drug-prodrug transformation impacting PK.
www.biorxiv.org/content/10.6...
We are looking for an enthusiastic intern (100%) to work on extending our high-throughput metabolic fingerprinting platform into 3D cancer models, such as spheroids and organoids.
Please apply here: jobs.unibas.ch/offene-stell...
www.biorxiv.org
The Department of Biomedicine is a joint effort between the University of Basel and the University Hospitals Basel. It unites basic and clinical scientists to advance our understanding of health and d...
We discussed in our past journal club how Benztropine, a Parkinson’s drug, limits intracellular mycobacterium tuberculosis growth by modulating host histamine receptor H1, highlighting histamine signalling as a host-directed target.
www.nature.com/articles/s44...
Impressive and interesting talks this week from our lab at the DBM monthly seminar series!
Sebastian Bors and Tobias Fuhrer presented their projects and preliminary results, illustrating our lab's efforts to combine large screens with cell culture and high-throughput metabolomics.
Welcome, Tuomas Lindeman, as a new PhD student in our lab!
Tuomas will be working fast targeted LC-MS/MS methods to expand our analytical portfolio for large clinical sample cohorts.
🎉 We’re excited to announce that Laurentz has been awarded the Research Fund for Excellent Junior Researchers 2025 of the University of Basel.
As part of this project, we are now looking for a motivated intern: jobs.unibas.ch/offene-stell...
The Zampieri Lab at the University of Basel is recruiting a highly motivated PhD candidate to investigate how metabolic programs drive cancer metastasis.
📩 Only applications submitted through the official recruiting system of the University of Basel will be considered.
jobs.unibas.ch/offene-stell...
We have multiple open positions in our lab (www.zampierilab.org). Interested candidates should apply through the University of Basel’s official recruitment portal:
www.unibas.ch/en/Working-a...
After our hike up the hills in Pratteln, we had a lovely evening out at Wystübli Leuengrund, enjoying a lot of 🧀 fondue and local wine 🥂.
npj Antimicrobials and Resistance - The Parkinson’s drug benztropine possesses histamine receptor 1-dependent host-directed antimicrobial activity against Mycobacterium tuberculosis
The Department of Biomedicine is a joint effort between the University of Basel and the University Hospitals Basel. It unites basic and clinical scientists to advance our understanding of health and d...
The Department of Biomedicine is a joint effort between the University of Basel and the University Hospitals Basel. It unites basic and clinical scientists to advance our understanding of health and d...
By studying fundamental mechanisms regulating short- and long-term metabolic adaptation to genetic and chemical perturbations, our lab aims at finding new and unconventional therapeutic strategies, fr...