Excited to share our new review in Trends in Neuroscience with Gouki Okazawa @gouki-okazawa.bsky.social :
"The 'neat' and 'messy' in task-dependent neural geometry and computation"
where we reviewed what we know about the 'task-manager' in the brain.
A thread 👇
New review with Cheng Xue at U Chicago @cxue.bsky.social in Trends [email protected]! We discuss the neural geometry of task-dependent computation: disentangled encoding, RNN modeling, switch cost, etc.
www.cell.com/trends/neuro...
The ‘neat’ and ‘messy’ in task-dependent neural geometry and computation
by Cheng Xue @cxue.bsky.social & Gouki Okazawa @gouki-okazawa.bsky.social
www.cell.com/trends/neuro...
Made an AI-curated primate ephys literature database covering ~10000 papers with recording brain regions and target functions. Maybe useful for something.
okazawagouki.github.io/NHPLit/repor...
From the top of my head, here some recent ones:
"Two views on the cognitive brain" by @johnwkrakauer.bsky.social, @dlbarack.bsky.social
"Reconstructing computational system dynamics from neural data with recurrent neural networks" by @durstewitzlab.bsky.social et al
1/3
The basal ganglia output is often framed as a motor gate: corticostriatal circuits select an action, then GPi/SNr-thalamus helps release it. In humans, we find this same pathway carries cognitive variables embedded in movement signals—and even produces learning-relevant signals after feedback. 1/10
A mesoscale optogenetics system for precise and robust stimulation of the primate cortex
www.cell.com/neuron/abstr...
Task-similarity dependent reconfiguration of compositional modules and geometry in frontal cortex
www.biorxiv.org/content/10.1...
To solve diverse real-world tasks, the brain must flexibly switch between task rules
and adjust computations. Recent advances in analyzing neural data and modeling neural
networks have revealed their ...
www.cell.com
biorxiv.org
Task rules critically shape how neural populations encode information and generalize across cognitive demands, yet the mechanisms linking rule structure, neural dynamics, and behavior remain poorly un...
Li et al. present a microLED-based mesoscale optogenetic system for centimeter-scale,
million-pixel primate cortical stimulation. Optogenetically evoked saccades with accurate
retinotopic organization...
Population-level temporal decoding and dynamical structure in frontostriatal circuits during decision making
www.biorxiv.org/content/10.1...
Gouki Okazawa
Trends in Neurosciences
Gouki Okazawa
Cheng Xue
Dennis London
Gouki Okazawa
Gouki Okazawa
Joao Barbosa
Perceptual decisions unfold over time, requiring neural circuits to evaluate sensory evidence, track elapsed time, and commit to an action. To investigate how these computations are distributed across...
I’m building a foundational reading list for our lab (systems & circuit neuroscience, compneuro, modeling, neuromodulators, population coding etc.).
I’d like to crowdsource recommendations.
Which review(s) would you consider mandatory reading for the next generation of researchers?
