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Made an AI-curated primate ephys literature database covering ~10000 papers with recording brain regions and target functions. Maybe useful for something. okazawagouki.github.io/NHPLit/repor...
19d
A mesoscale optogenetics system for precise and robust stimulation of the primate cortex www.cell.com/neuron/abstr...
4mo
Gouki Okazawa
Task-similarity dependent reconfiguration of compositional modules and geometry in frontal cortex www.biorxiv.org/content/10.1...
New review with Cheng Xue at U Chicago @cxue.bsky.social in Trends [email protected]! We discuss the neural geometry of task-dependent computation: disentangled encoding, RNN modeling, switch cost, etc. www.cell.com/trends/neuro...
Population-level temporal decoding and dynamical structure in frontostriatal circuits during decision making www.biorxiv.org/content/10.1...
Excited to share our new review in Trends in Neuroscience with Gouki Okazawa @gouki-okazawa.bsky.social : "The 'neat' and 'messy' in task-dependent neural geometry and computation" where we reviewed what we know about the 'task-manager' in the brain. A thread 👇
5mo
12d
6mo
11d
Gouki Okazawa
The ‘neat’ and ‘messy’ in task-dependent neural geometry and computation by Cheng Xue @cxue.bsky.social & Gouki Okazawa @gouki-okazawa.bsky.social www.cell.com/trends/neuro...
To solve diverse real-world tasks, the brain must flexibly switch between task rules and adjust computations. Recent advances in analyzing neural data and modeling neural networks have revealed their ...
The ‘neat’ and ‘messy’ in task-dependent neural geometry and computation
www.cell.com
Final paper of my PhD 🤗 www.nature.com/articles/s44... There is growing interest in how cognitive control may improve value-based decision making. However, we find that a recent paper overestimated the role of control in their task, leading to erroneous interpretations of dACC recordings.
The basal ganglia output is often framed as a motor gate: corticostriatal circuits select an action, then GPi/SNr-thalamus helps release it. In humans, we find this same pathway carries cognitive variables embedded in movement signals—and even produces learning-relevant signals after feedback. 1/10
14d
Gouki Okazawa
Gouki Okazawa
Gouki Okazawa
4mo
From the top of my head, here some recent ones: "Two views on the cognitive brain" by @johnwkrakauer.bsky.social, @dlbarack.bsky.social "Reconstructing computational system dynamics from neural data with recurrent neural networks" by @durstewitzlab.bsky.social et al 1/3
3mo
3mo
biorxiv.org
Cheng Xue
Trends in Neurosciences
Dennis London
Harrison Ritz
Joao Barbosa
Li et al. present a microLED-based mesoscale optogenetic system for centimeter-scale, million-pixel primate cortical stimulation. Optogenetically evoked saccades with accurate retinotopic organization...
www.cell.com
A mesoscale optogenetics system for precise and robust stimulation of the primate cortex
www.nature.com
In a new computational analysis of previous work, this study shows that a control-free mechanism better accounts for value-based decisions than an account that assumes top-down control invigorating th...
Misspecified models create the appearance of adaptive control during value-based choice - Communications Psychology
www.biorxiv.org
Perceptual decisions unfold over time, requiring neural circuits to evaluate sensory evidence, track elapsed time, and commit to an action. To investigate how these computations are distributed across...
Population-level temporal decoding and dynamical structure in frontostriatal circuits during decision making
Task rules critically shape how neural populations encode information and generalize across cognitive demands, yet the mechanisms linking rule structure, neural dynamics, and behavior remain poorly un...
www.biorxiv.org
Task-similarity dependent reconfiguration of compositional modules and geometry in frontal cortex
I’m building a foundational reading list for our lab (systems & circuit neuroscience, compneuro, modeling, neuromodulators, population coding etc.). I’d like to crowdsource recommendations. Which review(s) would you consider mandatory reading for the next generation of researchers?
3mo
Nikolas Karalis