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Drug failure can still teach biology. BIIB078 worsened a neurodegeneration marker in ALS, anti-TIGIT promise faded in phase III, and Glybera worked but vanished on cost. www.nature.com/articles/d41...
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When drug discovery fails: scientists share their frustrations with the process
www.nature.com
In clinical trials, there are many times (and ways) a therapeutic can come up short.
Jon Douglas