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A new study, led by Kushal (Berkeley), Nicole&Victoria (UCSF) in full collaboration with @karthikshekhar.bsky.social, "Molecular and spatial analysis of ganglion cells on retinal flatmounts identifies perivascular neurons resilient to glaucoma" sciencedirect.com/science/arti... #retina #MERFISH
10mo
Xin Duan
A collaborative paper with Ge/Wei/Scanziani @hhmi-science.bsky.social integrating our anterograde trans-neuronal tracer (mWGA-mCherry, PMID: 35524141) with MERFISH to decode higher visual circuits (aka. reciprocal circuits) #Braininitiative #Brainconnects #vision www.biorxiv.org/content/10.6...
10mo
Online now:
11mo
4d
A recent review from Mahima Bose and the lab at COIN: "A neurobiology perspective on the assembly of retinal vasculature from 2D to 3D" #retina #neurovascular #neurobiology #Piezo2 #development #neurodegeneration #vascularbiology sciencedirect.com/science/arti...
Nimkar and colleagues present a flatmount spatial transcriptomics platform for mapping the distribution of retinal ganglion cell (RGC) types. The analysis uncovers systematic topographic biases among RGC types and identifies perivascular RGC types surviving preferentially after experimental glaucoma. The results highlight neuroprotective roles of perivascular niche in the retina.
dlvr.it
Molecular and spatial analysis of ganglion cells on retinal flatmounts identifies perivascular neurons resilient to glaucoma
@natrevneuro.nature.com just published a beautiful cover for the issue that includes the recent review on analogies in the visual system of vertebrates and invertebrates (@ryosuketanaka.bsky.social). Read it here doi.org/10.1038/s415... Science and Art, what could be better?
How do bottom-up and top-down thalamic inputs map onto the rich cellular taxonomy of the visual cortex? We combined transsynaptic tracing with spatial transcriptomics to find out. Our new preprint reveals a cellular framework for cortical hierarchy: www.biorxiv.org/content/10.6...
3d
11mo
Neuron
Xin Duan
Xin Duan
Xinxin Ge
Portugues Lab
The hierarchical organization of sensory cortices and the rich molecular taxonomy of their cell types are defining features of the mammalian cortex. Cortical areas along this hierarchy are reciprocall...
www.biorxiv.org
The Logic of Thalamic Inputs onto the Molecular Taxonomy of Cortical Neurons Reveals a Visual Hierarchy
The hierarchical organization of sensory cortices and the rich molecular taxonomy of their cell types are defining features of the mammalian cortex. Cortical areas along this hierarchy are reciprocall...
www.biorxiv.org
The Logic of Thalamic Inputs onto the Molecular Taxonomy of Cortical Neurons Reveals a Visual Hierarchy