A new study, led by Kushal (Berkeley), Nicole&Victoria (UCSF) in full collaboration with @karthikshekhar.bsky.social, "Molecular and spatial analysis of ganglion cells on retinal flatmounts identifies perivascular neurons resilient to glaucoma" sciencedirect.com/science/arti... #retina #MERFISH
A recent review from Mahima Bose and the lab at COIN: "A neurobiology perspective on the assembly of retinal vasculature from 2D to 3D" #retina #neurovascular #neurobiology #Piezo2 #development #neurodegeneration #vascularbiology sciencedirect.com/science/arti...
Nimkar and colleagues present a flatmount spatial transcriptomics platform for mapping the distribution of retinal ganglion cell (RGC) types. The analysis uncovers systematic topographic biases among RGC types and identifies perivascular RGC types surviving preferentially after experimental glaucoma. The results highlight neuroprotective roles of perivascular niche in the retina.
How do bottom-up and top-down thalamic inputs map onto the rich cellular taxonomy of the visual cortex? We combined transsynaptic tracing with spatial transcriptomics to find out. Our new preprint reveals a cellular framework for cortical hierarchy: www.biorxiv.org/content/10.6...
Neuron
Xin Duan
Xin Duan
Xinxin Ge
Portugues Lab
The hierarchical organization of sensory cortices and the rich molecular taxonomy of their cell types are defining features of the mammalian cortex. Cortical areas along this hierarchy are reciprocall...
The hierarchical organization of sensory cortices and the rich molecular taxonomy of their cell types are defining features of the mammalian cortex. Cortical areas along this hierarchy are reciprocall...