Sometimes ago Tom @tommclean.bsky.social uncovered a mechanism of bacterial gene regulation based on a clamp sliding and locking in a multi-drug resistance plasmid, RK2.
www.nature.com/articles/s41...
www.nature.com
Structural and single-molecule analyses show the CTPase, KorB, is a sliding DNA clamp that interacts with a clamp-locking protein KorA to inhibit gene expression over distances of more than 1 kb in th...
