Understanding where genomics models work and fail will be critical to their successful deployment. Meta models can tell us this, and give some insight into failure modes.
3/3 for @muntakimrafi.bsky.social this week. CSHL AIxBIO to boot (sorry to miss!) What a week!
Carl de Boer
1/11 Seq2exp models can predict how any DNA variant changes gene exp.However, in reality,sometimes they nail it,sometime sthey get the direction flat wrong (true for every model).Right now you have no way to tell which is which for any single prediction. So we built one (gRely)