Excited to share our latest review in #CircRes! We discuss current knowledge of #extracellular #mitochondria forms, mechanisms of release, and #pathophysiological relevance. Great work by Laura Pena and Magda Makuch in leading this effort!
www.ahajournals.org/doi/10.1161/...
#Mitochondria
This is crazy!
Do not miss this great issue on #extracellular #mitochondria in ❤ #cardiovascular patho-physiology‼️ Great opportunity to catch up with literature and very interesting insights from leaders in the field. 👀
www.ahajournals.org/doi/10.1161/...
NicolasAvilaLab
The basic sciences are HIRING at UCSF: open recruitment in the Department of Biochemistry & Biophysics. Please share and please apply! aprecruit.ucsf.edu/JPF05702
NicolasAvilaLab
A new model of #TumorNecrosis👹
Tumor CXCL1➡️myeloid skewing➡️
Ly6C-low Neutrophil forms intravascular #NeutrophilExtracellularTrap➡️
Intratumoral vascular occlusion➡️
Pleomorphic Necrosis-to-Metastasis
a role of TGFβ
@adrover.bsky.social @megeblad.bsky.social Nature 2025
www.nature.com/articles/s41...
NicolasAvilaLab
University of California, San Francisco is hiring. Apply now!
Blocking interleukin-6 to prevent the inflammation underpinning cardiovascular disease, genetically informed, without increased risk of infection
www.nature.com/articles/s44...
www.nature.com/articles/s44...
Here we study the origin of the cardiac cell lineages in the mouse embryo. Separate but coordinated lineages independently specified at gastrulation generate the myocardium and endocardium. Credits: Miquel Sendra & coll: Jorge Dominguez, K. McDole and L. Guinard
authors.elsevier.com/sd/article/S...
Excited to announce our new study (w/ @maxkrummel.bsky.social) published today @nature.com: Macrophages “hold our living identities” by taking tiny bites from living cells and presenting this information to CD8 T cells.
www.nature.com/articles/s41...
#immunology #cellbiology @immunox.bsky.social
Abby Buchwalter
I’m happy to share our latest work on tumour necrosis! During my time in the @megeblad.bsky.social lab, we found that tumour necrosis is not a passive phenomenon secondary to tumour growth, but an active phenomenon driven by neutrophils and NETs! Thread below: (1/13)
www.nature.com/articles/s41...
Inflammatory mischief managed: How retinoic acid calms heart attacks at the (marrow) source | Science Immunology www.science.org/doi/10.1126/...
Macrophages can sample antigens from living cells through a trogocytosis-like mechanism that routes ingested material away from degradation, a finding that delineates a previously unknown pathway...
