Hello world! Kicking off my first post with some exciting news 📣 Our study on tobacco smoke-induced mutagenesis in head & neck cancer (HNC) is out today in
@naturegenet.bsky.social! rdcu.be/efNiH 🧬🔥
We uncover the multiple ways tobacco and alcohol drive HNC development. A short thread 🧵⬇️
#PCBCommunity |🍰 Aquest matí, els #PCBakers han celebrat l’ #Endorfest en suport de la investigació per l’ #endometriosi, una malaltia ginecològica que afecta el 10% de les dones en edat fèrtil a Espanya🌸. Els fons recaptats es destinaran a la recerca que porta a terme @hospitalclinic.bsky.social 🤝
Interested in a PhD Fellowship in our Lab?
Check out the new #IRBBarcelona call:
Our team at #EMBLCanGen in Heidelberg!
Raquel Blanco gave a brilliant talk, and we had great poster presentations from Elisabet Figuerola, Olivia Dove, Ferran Muiños, Rocio Chamorro, and Axel Rosendahl. 👏
Thanks to @events.embl.org for organizing such a high-quality event in Cancer Genomics!
rdcu.be
Nature Genetics - Whole-genome sequencing and mutational signature analysis of 265 head and neck cancer samples collected from eight different countries provide insight into the vital contribution...
Looking for your next career move in science? We are #hiring! Discover our latest job and #PhD opportunities!
#Jobs ➡️ bit.ly/irbjobs
PhD General call ➡️ https://bit.ly/3LtzIXi
PhD IRB DRIVE call ➡️ https://bit.ly/4hODx5B
#IRBJobs #ScienceJobs #Jobs #JobOffer #JobOffers #OncoSky #AcademicSky
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Barcelona Biomedical Genomics Lab
Barcelona Biomedical Genomics Lab
Parc Científic de Barcelona
Laura Torrens
IRB Barcelona
🧪 Out in @nature.com: Smoking and biological sex shape healthy bladder tissue evolution, offering clues to #cancer risk.
✍️ #IRBBarcelona & University of Washington
➡️ bit.ly/42wcIN5
📌 DOI: 10.1038/s41586-025-09521-x
#IRBScience #CancerResearch #BladderCancer @bbglab.bsky.social
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IRB Barcelona
Very excited to share our new paper on the influence of biological sex and smoking in the clonal landscape of normal human bladder, just published in Nature.
A big thank you and congrats to all the authors, specially to @raquelbmi.bsky.social for all the shared efforts in this journey!
⬇️More info⬇️
So grateful to all the entire team, especially Jaume Mora, Sara Sánchez-Molina and Carla Ríos at @sjdhospitalbarcelona.org as well as collaborators!
Today our colleague Bet Figuerola @efigbo.bsky.social , presented her work on the genomics analysis of a singular cancer patient at the Node Seminar session of #IRBBarcelona.
Genomics helps us to understand the origins and evolution of cancer contributing to knowledge with possible clinical impact.
Ferriol Calvet
‼️ The final version of our study on the role of KDM6A/B in Ewing sarcoma is now out!! 🎉
Check it out here: aacrjournals.org/cancerres/ar...
📢 Thrilled to share our latest paper, KDM6 Demethylases Contribute to EWSR1::FLI1-Driven Oncogenic Reprogramming in Ewing Sarcoma, from my PhD, is now published in Cancer Research!
Explore our findings🔬🧬: aacrjournals.org/cancerres/ar...
#Epigenetics #Cancer #EwingSarcoma
Huge thanks to the team!
Barcelona Biomedical Genomics Lab
Abstract. Ewing Sarcoma (EwS) is a highly aggressive tumor arising in bones and soft tissues driven by the fusion oncoprotein EWSR1::FLI1. This aberrant transcription factor binds to GGAA microsatelli...
KDM6A and KDM6B mediate critical mechanisms behind EWSR1::FLI1 transcriptional activation program involving demethylase-independent and dependent functions, respectively, supporting the development of...
📢 Thrilled to share our latest paper, KDM6 Demethylases Contribute to EWSR1::FLI1-Driven Oncogenic Reprogramming in Ewing Sarcoma, from my PhD, is now published in Cancer Research!
Explore our findings🔬🧬: aacrjournals.org/cancerres/ar...
#Epigenetics #Cancer #EwingSarcoma
Huge thanks to the team!
aacrjournals.org
Abstract. Ewing Sarcoma (EwS) is a highly aggressive tumor arising in bones and soft tissues driven by the fusion oncoprotein EWSR1::FLI1. This aberrant transcription factor binds to GGAA microsatelli...
🚨 New paper alert!
Sex and smoking bias in the selection of somatic mutations in human bladder
www.nature.com/articles/s41...
by @raquelbmi.bsky.social, @ferriol.bsky.social et al (in collaboration with Rosana Risques lab in @uwmedicine.bsky.social)
🧬 Investigadores de @sjdhospitalbarcelona.org y del @crg.eu identifican nuevas dianas terapéuticas para el sarcoma de Ewing, un cáncer pediátrico muy agresivo.
🔗
Sex bias and association with smoking history identified in the landscape of driver mutations and clonal expansions in normal human bladder tissue may explain the higher bladder cancer risk in men and smokers.
Los resultados del estudio abren la puerta a desarrollar fármacos que inhiban específicamente las dos enzimas que activan genes relacionados con este cáncer.
