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Another amazing discovery from the Sternberg lab ๐Ÿ˜Š These RT based phage defense systems don't cease to amaze. This time with double RTs ๐Ÿ’• Can't wait to read this in detail. Congrats Megan, Kanta, Hiroshi & Sam et al! ๐Ÿป Great thread below โคต๏ธ
1mo
Avigail Stokar-Avihail
1/9 New preprint from the Sternberg Lab in collaboration with the Nishimasu Lab! We uncover how the DRT3 antiphage immune system pairs two reverse transcriptases, one RNA-templated and one protein-templated, to build a double-stranded DNA effector. doi.org/10.64898/202...
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Sternberg Lab