T3SS activity comes at a cost—bacteria that use the system pay with reduced growth. We found how Yersinia balance costs and benefits: at higher densities, they actively suppress T3SS activity and adhesion, switching from colonization to replication and dissemination.
doi.org/10.1371/jour...
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Author summary Bacteria can use the type III secretion system (T3SS), a molecular syringe-like device, to manipulate host cells by injecting effector proteins. Yersinia enterocolitica, a pathogenic ba...