One week left to apply for two 3-year postdocs in the lab on molecular mechanisms of Burkholderia pathogenesis. Posts associated with Magdalen College. Our lab is based in the Dunn School of Pathology with amazing collaborators at Oxford and MORU magdalencareers.pinpointhq.com/postings/c90...
Congrats @ainsley-beaton.bsky.social
Happy to share the last publication of @bobytaillefer.bsky.social, showing that #T6SS heterogeneity is an attenuation strategy to optimizes the trade-off between competitive killing and survival.
Congrats @natalia-los.bsky.social
Latest research from the lab out now. We examined the role and expression of fimbriae during UPEC bloodstream infection. A real team effort and brilliant collaboration with Mark Schembri’s lab in Brisbane. Thanks to the MRC and BBSRC for supporting our research @ukri.org
Job Opening: Calleva Centre Postdoctoral Researchers- The deadly enigma of melioidosis: Decoding the pathogenesis of Burkholderia pseudomallei. at Magdalen College in Central Oxford.
As an editor at the Biochemical Journal, I'd love to see more papers submitted in the areas of bacterial immune systems / CRISPR / archaeal molecular biology / nucleic acid processing enzymes
Cascales Lab
Teresa Thurston
Opportunity for someone interested in a full time permanent lectureship in Environmental Microbiology and Biotechnology at @uccmicrobiology.bsky.social
www.jobs.ac.uk/job/DRS979/l...
A phage-derived particle killed more than 90% of STEC O157 strains via CRISPR-Cas targeting stx, reducing bacterial loads and symptoms in animals.
Author summary Extraintestinal pathogenic Escherichia coli (ExPEC) colonise the human gut without causing disease but can disseminate to the urinary tract and bloodstream. Understanding the mechanisms...
journals.plos.org
James Connolly
Now online. Great collaboration with the Tidow lab @seegerlab and the @embl SAXS beamline.
Capturing transient states of heterodimeric ABC transporter TM287/288 by time-resolved small-angle X-ray scattering: Biophysical Journal www.cell.com/biophysj/ful...
Also of potential interest to #UTISky followers
James Connolly
The T6SS is a widespread nanoweapon deployed by #bacteria, but why is it deployed heterogeneously? @cascaleslab.bsky.social &co show that #Ecoli adopt distinct #T6SS attacker "ON" & defender "OFF" roles to optimize survival, a key strategy in microbial warfare @plosbiology.org 🧪 plos.io/3S5dL45
Structures of the heterodimeric ATP-binding cassette (ABC) transporter TM287/288 have
previously been determined in several states indicating large conformational changes
during its reaction cycle. Ho...
Really pleased to finally see this out! More insights into the global regulator MtrA and how it helps S. ven sense and respond to its environment.
Malcolm White
Prof Jenny Rohn
David Clarke
Kesha Josts
PLOS Biology
Discover an exciting academic career path as a Lecturer (Above the Bar) in Environmental Microbiology & Biotechnology at jobs.ac.uk. Don't miss out on this job opportunity - apply today!
First paper for PhD student in the Bolam / Lowe labs Natalia Łoś on a the characterisation of a new CBM family that binds (beta) mannan! #glycotime @natalia-los.bsky.social 🥳🥳
link.springer.com/article/10.1...
Ainsley Beaton
β-mannans are plant structural and storage polysaccharides prevalent in the human diet. Their degradation in the gastrointestinal tract is mediated by the human gut microbiota (HGM) through expression...
Researchers at our Read & Publish institutions can benefit from fee-free OA publishing and access to read content in our journals. Not sure if your institution has signed up? Check out the full list on our website: https://ow.ly/yeH150Z0THn 🧪
Lis Lowe
Great to see this published in the @microbiologysociety.org collection on Actinomycetes
Conserved regulator MtrA directly activates ectoine biosynthesis and expression of BldM and WhiI to trigger sporulation in response to hyperosmotic stress
www.microbiologyresearch.org/content/jour...
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www.microbiologyresearch.org
The MtrAB two-component system is a master regulator of antibiotic biosynthesis in Streptomyces species. MtrA is also required for sporulation under certain growth conditions, which means that on some...
Out Now! Genome-scale metabolic modelling identifies vaginal microbiome members as potential probiotics #MicroSky
Nature Microbiology
Nature Microbiology, Published online: 12 June 2026; doi:10.1038/s41564-026-02380-wMetabolic modelling and experimental validation reveal that current probiotics lack the functional diversity of native microbes, identifying vaginal species that inhibit Gardnerella vaginalis through the dual mechanisms of resource competition and d-lactic acid production.
