Pathologists have used nuclear & tissue shapes to diagnose #cancer for decades, but what is the molecular basis for this? In our latest work, we develop a computational pipeline to figure this out in #colorectalcancer! Check out 🧵& preprint #mechanobiology #stemcells www.biorxiv.org/content/10.1...
New preprint
We identify a conserved intramolecular interaction in KANK proteins.
We show that the KANK KN domain contains separable functional modules: the LD motif mediates talin binding, while residues 60-68 mediate interaction with the KANK ankyrin repeat domain
doi.org/10.64898/202...
We hire!
The CytoMorpho Lab is looking for an engineer with a background in cell and molecular biology to join our team in Paris. This is a 18-month contract position, but we're open to exploring long-term opportunities.
More details here:
cytomorpholab.com/index.php/jo...
Almost 40 years later, has anyone identified what "buttonin", the 75-kD protein that decorates microtubule like buttons, is? dx.doi.org/10.1083/jcb.104.6.1553
Okay want to talk blebs, migration, life and more!!! I will be at poster session (sunday) at 2 PM at poster board- 247 at @ascbiology.bsky.social #Cellbio2025