📜The final version of our paper on eCIS firing is out:
www.nature.com/articles/s41...
Congrats to @xujwet.bsky.social @chipericson.bsky.social
#cryoEM #CIS
Bacterial contractile injection systems (CIS) mediates cell-cell contacts, but the firing mechanism is unclear. Here, the authors employ a multimodal cryoEM approach and structure guided engineering t...
🧐Checkout our preprint revealing the stepwise firing💥 mechanism of a Contractile Injection System @xujwet.bsky.social&@chipericson.bsky.social trapped the complex by structure-guided engineering🧪 in multiple intermediate states and imaged them by multimodal #cryoEM❄️🔬
www.biorxiv.org/content/10.1...