Microbial cell-cell interactions | contractile injection systems | cytoskeleton | evolution | multiscale imaging | ETH Zürich
- run by lab members -
Pilhofer Lab 🦠❄️🔬
Loading...
New paper alert!! We just discovered a new filament system that is widespread exclusively within CPR bacteria! www.biorxiv.org/content/10.6.... Short thread below. 🦠🔬🚀
CPR bacteria form a superphylum that may account for 15–50% of all bacterial diversity (!!), yet we know remarkably little about them. Recently, we showed that the dwarf CPR bacterium JR1 entangles its host with specialized filaments and kills using a lance-like structure. 🦠⚔️
Our paper "Gene ancestries reveal diverse microbial associations during eukaryogenesis.” is finally out in Nature.
Eukaryogenesis was likely a gradual process shaped by multiple microbial partners and virus-mediated gene transfer, rather than a single binary symbiosis.
doi.org/10.1038/s415...
Congratulations to Gautam Dey (EMBL) and Omaya Dudin (University of Geneva) for being awarded the EMBO Gold Medal 2026 in recognition of their outstanding contributions to the #LifeSciences in Europe! 🧪 https://www.embo.org/press-releases/embo-gold-medal-2026-awarded-to-gautam-dey-and-omaya-dudin/
Every year, D-BIOL welcomes high school students for an immersive study week, this year 24 of them in 7 different projects!
From hands-on lab work to discovering cutting-edge research, it’s all about inspiring the next generation of molecular biologists.
#BioETH #StudyWeek #StemEducation
The results here re 3D classification are quite impressive. Would be interesting to see how much the LPP improves classification of near-native samples with extreme compositional heterogeneity (e.g. derived from cellular fractions)
"Humbled to receive this recognition. This belongs as much to my team, my family, & to my home, Palestine: the people, the place, the joyful stubbornness to enjoy life."
Cheers buddy @gautamdey.bsky.social
Thx to my mentors @sophiemartinlab.bsky.social, @paveltomancak.bsky.social, & Pierre Gönczy.
Reminder — UW #Microbiology has an open search for an Assistant Professor, focusing on fundamental problems in #bacteriology!
If you or someone you know would be suitable, here's the ad:
apply.interfolio.com/185622
Jon Chen @jonchenjk.bsky.social and Claris Chong's review of recent in situ cryo-ET chromatin studies and our opinion on an important future genomic direction is now published in Current Opinions in Structural Biology.
www.sciencedirect.com/science/arti...
Video
Exciting PhD position available in the Diepold lab @kit.edu ! We're especially interested in international students with expertise in molecular biology and ready to lead a cutting-edge research project in molecular machines and infection biology. Find out more at diepoldlab.com.
The Candidate Phyla Radiation (CPR) represents a bacterial superphylum estimated to include between 15–50% of all bacterial species, yet CPR bacteria remain challenging to culture and have been primar...
Phase plates can in principle overcome the poor image contrast in electron cryo–microscopy (cryo-EM) and the resulting limits on the structural reconstruction of small proteins. However, previous desi...
Congratulations to Gautam Dey (EMBL) and Omaya Dudin (University of Geneva) for being awarded the EMBO Gold Medal 2026 in recognition of their outstanding contributions to the #LifeSciences in Europe! 🧪 https://www.embo.org/press-releases/embo-gold-medal-2026-awarded-to-gautam-dey-and-omaya-dudin/
Diepold Lab
In a series of 3 papers and preprints, we’re thrilled to share with you the working laser phase plate. In collaboration with research led by Holger Müller at UC Berkeley, this is a huge innovation in imaging to make small and faint objects inside cells visible. bit.ly/4vK9LVn
